5TH SEM MEDICINAL CHEMISTRY
ASSIGNMENT-3
Prepared by: Ms. Mitali H. Jasani
HISTORY OF MEDICINAL
CHEMISTRY
- Write a note on development of Medicinal Chemistry.05
- What is Medicinal Chemistry? Give importance of Medicinal chemistry in drug discovery.05
- What is Medicinal Chemistry? Give importance of Medicinal chemist in drug development.06
PHYSICO-CHEMICAL
PROPERTIES
- Write a short note on following: Bioisosterism 04
- What are Isomers? Draw the structure of one drug each having Optical isomerism and Geometrical isomerism.05
- What is eudismic ratio? Give importance of Chirality in drug action. 05
- Write a note on geometric & optical isomerism.05
- Explain the physicochemical parameters affecting drug absorption. 06
- What are Physiological properties? Explain Partition coefficient and Protein binding in detail.05
- Explain the effect of following parameter on biological activity.05
- 1). Complexation 2). Hydrogen bonding
- Enumerate the physicochemical properties affecting biological activity. Explain Hydrogen bonding properties in detail. 06
- Define Bioisosterism. How they are useful in designing new drug.06
- Write a note on Partition coefficient and Ionization that affect biological activity.06
- Write a short note on Bioisosterism.05
- How Isomerism affect the biological activity.06
