6TH SEM MEDICINAL CHEMISTRY ASSIGNMENT-2

6TH SEM MEDICINAL CHEMISTRY

ASSIGNMENT-2

Prepared by: Ms. Mitali H. Jasani

ANTI-PARKINSON’S AGENTS

1.      Write a note on antiparkinson’s agents. 05 III

2.      Why carbidopa is suggested with L-DOPA in Parkinson disease? 05II

RECEPTOR AND DRUG ACTION

1.      Classify receptors? Describes theories of drug receptor interaction in detailed. 06

2.      Explain the theory of receptors in detail.06

3.      Explain factors affecting the drug-receptor interactions05III

4.      What are receptors? Describe various forces involved in drug receptor interaction with examples. 05 III

6TH SEM MEDICINAL CHEMISTRY ASSIGNMENT-1 NSAIDS

6TH SEM MEDICINAL CHEMISTRY

ASSIGNMENT-1

Prepared by: Ms. Mitali H. Jasani

NSAIDS ANTI GOUT AND DMARDS

1. Explain NSAIDs in detail 05 
2. What are NSAIDs? Classify them with two examples of each class. Write synthesis of one non steroidal NSAID having one chiral center 06 II 
3. What are NSAIDs? Classify them with two examples of each class. Write the synthesis of Ibuprofen 06 
4. Write Mechanism of action, uses and side effect of NSAIDs 
5. Write the advantages of selective COX-2 inhibitors over non-selective 
6. NSAIDs. Classify NSAIDs and write MOA of Indomethacin 
7. JUSTIFY:Why Sulindac, a potent nonselective COX inhibitors, is said to have a lower risk of stomach bleeding and nephrotoxicity than other aspirinlike NSAIDs such as Indomethacin 02 
8. Write a note on drugs used in the management of Gout and Hyperuricemia. 
9. Write a note on anti-gout agents 
10. Write IUPAC name and synthesis AND USE of any two drugs : 06 

a) Diclofenac sodium b) Naproxen c) Mefenamic acid d) Ibuprofen e) Allopurinol f) diclofenac g) Paracetamol h) Aspirin i) Indomethacin