6TH SEM MEDICINAL CHEMISTRY
ASSIGNMENT-1
Prepared by: Ms. Mitali H. Jasani
NSAIDS ANTI GOUT AND
DMARDS
- Explain NSAIDs in detail 05
- What are NSAIDs? Classify them with two examples of each class. Write synthesis of one non steroidal NSAID having one chiral center 06 II
- What are NSAIDs? Classify them with two examples of each class. Write the synthesis of Ibuprofen 06
- Write Mechanism of action, uses and side effect of NSAIDs
- Write the advantages of selective COX-2 inhibitors over non-selective
- NSAIDs. Classify NSAIDs and write MOA of Indomethacin
- JUSTIFY:Why Sulindac, a potent nonselective COX inhibitors, is said to have a lower risk of stomach bleeding and nephrotoxicity than other aspirinlike NSAIDs such as Indomethacin 02
- Write a note on drugs used in the management of Gout and Hyperuricemia.
- Write a note on anti-gout agents
- Write IUPAC name and synthesis AND USE of any two drugs : 06