3RD SEM PHARMACEUTICAL ORGANIC
CHEMISTRY-II
ASSIGNMENT-1
Prepared by: Ms. Mitali H. Jasani
1. Explain
the concept of aromaticity of benzene.
2. Discuss
kekule’s structure with evidence and limitation.
3.
Explain in detail
Friedel craft alkylation and acylation in detail with mechanism.
4.
Explain in detail
halogenation in detail with mechanism.
5.
Explain in detail
nitration in detail with mechanism.
6.
Explain in detail
sulphonation in detail with mechanism.
7.
Explain in detail
Friedel craft alkylation and acylation in detail with mechanism
8.
Give Reimer-Tiemann Reaction and Fries Rearrangement in
Detail.
9.
Explain chemical properties of phenol.
10.
Explain chemical properties of aromatic amine.
11. Explain Basicity of Amine
and Effect of Substituent on Basicity of Amine.
12. Explain acidity of phenol and Effect of Substituent on
acidity of phenol.
13. Explain acidity of aromatic acidl and Effect of Substituent
on acidity of aromatic acid.
14. Discuss effect of
substituent on reactivity and orientation of mono substituted benzene compound
towards electrophilic substitution reaction.
15. Explain chemical properties
of benzoic acid.
16. Explain synthetic
application of aryl diazonium salt.
